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Research PaperResearchia:202610.07018

Language-model ratings of depression reflect the rater more than the patient

Baihan Lin

Abstract

Depression has no diagnostic blood test. Language models promise tireless, consistent assessment, but can accurate raters disagree about individuals? We pre-registered 880 language-model raters, crossing 11 open models with prompting and scoring choices, and applied them to 189 interviews against the eight-item Patient Health Questionnaire. Model choice explained 30.0% of summed-symptom score variance, stable participant differences 10.5%. Two randomly drawn raters with area under the receiver o...

Submitted: October 7, 2026Subjects: Neuroscience; Neuroscience

Description / Details

Depression has no diagnostic blood test. Language models promise tireless, consistent assessment, but can accurate raters disagree about individuals? We pre-registered 880 language-model raters, crossing 11 open models with prompting and scoring choices, and applied them to 189 interviews against the eight-item Patient Health Questionnaire. Model choice explained 30.0% of summed-symptom score variance, stable participant differences 10.5%. Two randomly drawn raters with area under the receiver operating characteristic curve (AUC) >= 0.70 disagreed on screening decisions for 40% of participants, on average. Average over-rating governed how many were flagged, yet equal-capacity raters chose differently for about one participant in five. A locked analysis of 86 new interviews reproduced the main pre-registered findings. Exploratory recalibration with 40 labelled participants raised accuracy from about 60% to 75% and halved disagreement, leaving one participant in five decided differently. Calibration repaired much of the rater dependence without securing agreement about individuals.


Source: arXiv:2610.08501v1 - http://arxiv.org/abs/2610.08501v1 PDF: https://arxiv.org/pdf/2610.08501v1 Original Link: http://arxiv.org/abs/2610.08501v1

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Date:
Oct 7, 2026
Topic:
Neuroscience
Area:
Neuroscience
Comments:
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