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Research PaperResearchia:202607.16041

TCAM-Diff: Triplane-Aware Cross-Attention Medical Diffusion Model

Zhenkai Zhang

Abstract

We introduce TCAM-Diff, a novel 3D medical image generation model that reduces the memory requirements to encode and generate high-resolution 3D data. This model utilizes a decoder-only autoencoder method to learn triplane representation from dense volume and leverages generalization operations to prevent overfitting. Subsequently, it uses a triplane-aware cross-attention diffusion model to learn and integrate these features effectively. Furthermore, the features generated by the diffusion model...

Submitted: July 16, 2026Subjects: Engineering; Biomedical Engineering

Description / Details

We introduce TCAM-Diff, a novel 3D medical image generation model that reduces the memory requirements to encode and generate high-resolution 3D data. This model utilizes a decoder-only autoencoder method to learn triplane representation from dense volume and leverages generalization operations to prevent overfitting. Subsequently, it uses a triplane-aware cross-attention diffusion model to learn and integrate these features effectively. Furthermore, the features generated by the diffusion model can be rapidly transformed into 3D volumes using a pre-trained decoder module. Our experiments on three different scales of medical datasets, BrainTumour 128 x 128 x 128, Pancreas 256 x 256 x 256, and Colon 512 x 512 x 512, demonstrate outstanding results. We utilized MSE and SSIM to assess reconstruction quality and leveraged the Wasserstein Generative Adversarial Network (W-GAN) critic to assess generative quality. Comparisons with existing approaches show that our method gives better reconstruction and generation results than other encoder-decoder methods with similar-sized latent spaces.


Source: arXiv:2607.13812v1 - http://arxiv.org/abs/2607.13812v1 PDF: https://arxiv.org/pdf/2607.13812v1 Original Link: http://arxiv.org/abs/2607.13812v1

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Submission Info
Date:
Jul 16, 2026
Topic:
Biomedical Engineering
Area:
Engineering
Comments:
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